| abstract |
HISTANIN-3 RECEPTOR ANTAGONISTS The present invention is directed to a compound of formula 1 as defined herein or to a pharmaceutically acceptable salt thereof; to a pharmaceutical composition containing a compound of formula 1, to a process of preparing a compound of formula 1.0 to using a compound of formula 1 to prepare a medicament for treating a disorder or condition that can be treated by antagonizing it. histamine-H3 receptors, and the use of the compound of formula 1 for the preparation of a medicament for treating a disorder or condition selected from the group consisting of depression, mood disorders, schizophrenia, anxiety disorders, Alzheimer's disease, disorder Attention Deficit Hyperactivity Disorder (ADHD), Psychotic Disorders, Cognitive Disorders, Sleep Disorders, Obesity, Dizziness, Epilepsy, Movement Disease, Respiratory Tract Disease, Allergy, Allergy-Induced Airway Responses, Allergic Rhinitis, Nasal Congestion , allergic congestion, congestion, hypotension, cardiovascular disease, GI tract diseases, hyper and hypo motility, and secretion of the gastrointestinal tract. |