| abstract |
unpublished peptides for the treatment and prevention of disorders related to the immune system, including the treatment and prevention of infection by modulation of innate immunity. in one aspect, the present invention provides unpublished isolated peptides that can be used to modulate innate immunity in an individual and / or for the treatment of a disorder related to the immune system, including the treatment and prevention of infection by modulation of innate immunity . also provided are a peptide-reactive agent, a pharmaceutical composition that includes the peptide, an isolated nucleic acid molecule encoding the peptide, a recombinant nucleic acid construct that includes the nucleic acid molecule, at least one host cell comprising the construction of recombinant nucleic acid and a method of producing the peptide using the host cell. the present invention further provides a method for treating and / or preventing infection in an individual by administering the peptide of the invention to the individual, thereby modulating the innate immunity in the individual. in addition, the present invention provides a method for predicting whether an individual would respond to treatment with a peptide of the invention. |