Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dee814b1ba7fddffa2ecdea48bf074f4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2006-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01d7ee77eb8f5448a524cd3a0cdd93f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13f21b3d17681fd276e9957359a265ba |
publicationDate |
2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
BR-PI0616211-A2 |
titleOfInvention |
Methods for the diagnosis of pancreatic cancer |
abstract |
METHODS FOR THE DIAGNOSIS OF PANCREATIC CANCER. The present invention provides a method of identifying the origin of a metastasis of unknown origin by obtaining a sample containing metastatic cells; measurement of biomarkers associated with at least two different carcinomas; combination of biomarker data in an algorithm, in which the algorithm normalizes biomarkers against a reference; and imposing a cut-off value that optimizes the sensitivity and specificity of each biomarker, weighs the prevalence of carcinomas and selects a source tissue, determining the origin based on the highest probability determined by the algorithm, or determining that the carcinoma is not derived from a particular set of carcinomas; and, optionally, the measurement of specific biomarkers for one or more additional different carcinomas, and repetition of the steps for additional biomarkers. |
priorityDate |
2005-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |