http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0614850-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbadc41aa91592752369d88100f96411 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
| filingDate | 2006-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cd50bdca6d1e0a8a9e5a74d74a338c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e991725f77abfe1d588525fc8e88d35b |
| publicationDate | 2011-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0614850-A2 |
| titleOfInvention | proteolysis resistant antibody preparations |
| abstract | PREPARATIONS OF PROTEOLISE RESISTANT ANTIBODIES. Antibody preparations with substantially homogeneous and non-sialylated glycoforms such as GO and G2 are prepared by enzymatic treatment, expression under certain conditions, the use of particular host cells. and by contact with serum These antibody preparations resist cleavage by proteases such as papain, ficin, bromolein, pepsin, a metalloproteinase matrix such as MMP-7, neutrophil elastase (HNE), stromelysin (MMP). -3) and macrophage elastase (MMP-12), and glycation-modifying enzymes Antibody preparations with substantially homogeneous unsialylated glycoforms and testing methods for glycation in an antibody are useful with respect to characterization of the glycols. antibody properties and / or diseases or conditions characterized by an increase in protease activity. |
| priorityDate | 2005-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1001.