| abstract |
CARBOSILAN DENDRIMERS, THEIR PREPARATION PROCESSES, COMPOSITIONS AND KITS UNDERSTANDING THE SAME, USES OF THE REFERRED COMPOUNDS AND COMPOSITIONS IN DRUG MANUFACTURING. The present invention relates to new carbosilane dendrimers, their preparations and uses. The dendrimers of the invention have secondary, tertiary and quaternary amino groups at their branching ends. Its possible uses include vehicles to transport charged anionic molecules in the blood, such as nucleic acids, including ODN and RNAi, and other anionic drugs with which they have the ability to interact, protect them from interacting with plasma protein, and / or increase your penetration rate into target cells. In cases where the bond is long-lasting, the dendrimers of the invention can be used to attach anionic molecules to surfaces. Its uses also include its administration as active ingredients to prevent or treat diseases caused by microorganisms with whose structure and / or life cycle they interfere. |