http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0612628-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f874eb11d4775decc4fd06a6071a4c9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2006-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea5743b2a265ab8f4a4f3eb28f5c803e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe5523f7ed7f57ffeb0b64691494c685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3786984d24e5f88727e2ef1a9b89511d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4fe66ebcf403655600f33aaa9f0f782 |
| publicationDate | 2012-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0612628-A2 |
| titleOfInvention | 1- (2-Amine-3- (substituted alkyl) -3h-benzimidazolyl) methyl] -3-substituted-1,3-dihydro-benzoimidazole-2-one with activity on respiratory syncytial virus |
| abstract | 1- (2-AMINE-3- (SUBSTITUTED ALKYL) -3H-BENZIMIDAZOLYL) METHYL] -3-DIIDRO-BERNZ OIMIDAZOL-2-ONAS WITH RESPIRATORY SYNCHRONIZE VIRUS ACTIVITY. The present invention relates to RSV replication inhibitors of formula (I) which may be represented by formula (I), their chemically isomeric salts and stereo forms, where R is a radical of formula (a) or (b); Q is hydrogen or C1-6 alkyl optionally substituted by one heterocycle or Q is C1-6 alkyl substituted by both a radical -OR4 and a heterocycle; Alk is C 1-6 alkanediyl; X is O or S; -a ^ 1 ^ = aa ^ = 2 ^ -a ^ 3 ^ = a ^ 4 ^ is -N = CH-CH = CH-, -CH = N-CH = CH-, -CH = CH-N = CH or -CH = CH-CH = N-; R4 is Ar or heterocycle; R 2 is hydrogen, C 1-6 alkyl, C 1-6 substituted alkyl, C 3-7 cycloalkyl; R 13 is hydrogen, C 1-6 alkyl, cyano, aminecarbonyl, C 1-6 alkyl polyhalo, C 2-6 alkenyl or C 2-6 alkynyl; R4 is hydrogen or C1-6 alkyl; Ar is phenyl or substituted phenyl; Het is a heterocycle; pharmaceutical compositions containing compounds (I) and processes for preparing compounds (I). |
| priorityDate | 2005-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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