abstract |
OXINDOL DERIVATIVES, PHARMACEUTICAL PREPARATION, USE AND PROCESS FOR PRODUCTION OF SUCH DERIVATIVES. The invention relates to compounds of the general formula IA or the pharmaceutically acceptable salts thereof, R 1, R 2, R 4 and R 5 are described herein, a process for their manufacture, medicaments which may be used in the invention. contain as well as the use of these compounds as pharmaceutically active agents. The compounds show activity as antiproliferative agents and may be especially useful for treating cancer. |