abstract |
ANTIGENIC CONJUGATES AND USES OF THE SAME. The present invention is in the field of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) chained to at least one antigen of the invention, wherein said antigen of the invention is CCR5 of the invention, gastrin of the invention, CXCR4 of the invention, CETP of the invention or 05a of the invention. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular for the treatment of diseases in which the antigen of the invention mediates or contributes to the condition, particularly for the treatment of AIDS, gastrointestinal cancers, coronary heart disease or inflammatory diseases. . Furthermore, the compositions of the invention induce efficient immune reactions, in particular antibody reactions. In addition, the compositions of the invention are particularly useful for effectively inducing self-specific immune reactions within the indicated context. |