| abstract |
PHARMACEUTICAL FORMULATIONS TO MINIMIZE INTERACTION BETWEEN DRUGS. The present invention relates to a pharmaceutical combination for minimizing pharmacokinetic drug-drug interaction, including a first pharmaceutical component having a specific pharmacokinetic profile in a mammal, and a second pharmaceutical component formulated for parenteral administration, having an altered pharmacokinetic profile. different from the unchanged pharmacokinetic profile of the second pharmaceutical component, which would interfere with the pharmacokinetic profile of the first pharmaceutical component. Due to its altered pharmacokinetic profile, the second pharmaceutical component does not substantially affect the pharmacokinetic profile of the first pharmaceutical component. |