http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0611923-A2

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filingDate 2006-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8e6255b761393a2627503337a97cdcb
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publicationDate 2009-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0611923-A2
titleOfInvention Synergistic modulation of ftl3 kinase using aminoquinoline and aminoquinazoline kinase modulators
abstract SYNERGIC MODULATION OF FTL3 KINASE USING THE AMINOKINOLINE AND AMINOKINAZOLINE KINASE MODULATORS. The invention is directed to a method for inhibiting FLT3 tyrosine kinase activity or expression, or inducing or expressing FLT3 tyrosine kinase activity in a cell or subject comprising administering a farnesyl transferase inhibitor and a FLT3 kinase inhibitor selected from aminoquinoline and aminoquininozoline compounds of Formula (I '); wherein R1, R2, R2, R3, B, Z, Q, p, q and X are as defined herein in this patent application. Included within the present invention are both prophylactic methods and for treating a subject at risk of (or susceptible to) the development of cell proliferation disorder or a FTL3-related disorder.
priorityDate 2005-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 24.