abstract |
PURINE DERIVATIVES BY N2-QUINOLINE OR ISOQUINOLINE REPLACEMENT AND THEIR PREPARATION AND USES METHODS. A novel composition of the following formula is disclosed: wherein W represents a hydrogen, an optionally substituted C1-6-alkyl, an optionally substituted C1-6-cycloalkyl, or an optionally substituted C1-6-haloalkyl ; Y represents a hydrogen or a saccharide, Q represents a quinoline or an isoquinoline. Also disclosed is a pharmaceutical composition comprising the same, methods for treating cancer using it, and methods for the synthesis thereof. |