http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0611491-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-424 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 |
| filingDate | 2006-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198a34864813377b660eefb82cf18f70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b9509efe4a4c35528ac9fbb5a339e3 |
| publicationDate | 2010-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0611491-A2 |
| titleOfInvention | class d enzyme inhibition method in the treatment of a bacterial infection in a patient in need thereof; and method for treating bacterial infection or disease in a patient in need thereof |
| abstract | Method of inhibiting class D enzymes in the treatment of a bacterial infection in a patient in need of it; AND METHOD FOR TREATMENT OF BACTERIAL INFECTION OR DISEASE IN A NEEDED PATIENT. This invention relates to certain 6-alkylidene penem compounds, which act as a class D enzyme inhibitor. The β-lactamases hydrolyze the β-lactam antibiotics, and as such serve as a cause of resistance. bacterial. The compounds of the present invention, when combined with? -Lactam antibiotics, will provide effective treatment of life-threatening bacterial infections. In accordance with the present invention there are provided compounds of formula 1 which are useful for the treatment of bacterial infections having class D enzymes associated therewith: wherein: one of A and B denotes hydrogen and the other a heteroaryl group. optionally substituted fused tricyclic; and X is S or O. |
| priorityDate | 2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 489.