abstract |
For separation, removal, isolation, purification, characterization, identification or quantitation of plasminogen or a protein that is a plasminogen analogue, an affinity adsorbent is used which is a compound of formula II wherein one X is N and the other is N , C-Cl or C-CN; A is a support matrix optionally attached to the triazine ring by a separator; Z is O, S or N-R and R is H, C 1-6 alkyl, C 1-6 hydroxyalkyl, benzyl or? -Phenylethyl; B is an optionally substituted hydrocarbon bond containing from 1 to 10 carbon atoms; D is H, OH or a primary amino, secondary amino, tertiary amino, quaternary ammonium, imidazole, guanidino or amidino group; or B-D is -CHCOOH- (CH ~ 2-) ~ 3-4 ~ -NH ~ 2 ~; q is 2 to 6. |