abstract |
USE OF A COMPOUND, COMPOUND, PHARMACEUTICAL COMPOSITION, AND METHOD FOR PREPARING PHARMACEUTICAL COMPOSITIONS. The invention relates to dithiolethione derivatives as monoamino oxidase inhibitors, especially MAO-b inhibitors, methods for the preparation of these compounds and novel intermediates useful for the synthesis of said dithiolethione derivatives. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament which produces a beneficial effect. In embodiments of the invention the specific compounds disclosed herein are used for the production of a medicament useful in the treatment, amelioration or prevention of conditions associated with monoamine neurotransmission dysfunction. The compounds have the general formula (1) where symbols have the meanings given in the descriptive report. |