abstract |
3,4,5-SUBSTITUTED PIPERIDINE COMPOUNDS, USE AND PROCESS FOR PRODUCTION OF THE SAME AND PHARMACEUTICAL FORMULATION. The present invention relates to 3,4,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on the activity of refines; the use of a compound of this class for the preparation of a pharmaceutical formulation for the treatment of a disease dependent on renin activity; the use of a compound of this class in the treatment of a disease that depends on renin activity; pharmaceutical formulations comprising a 3,4,5-substituted piperidine compound, and / or a method of treatment comprising administering a 3,4,5-substituted piperidine compound, a method for the production of a 3,4,5-substituted piperidine compound, 5-substituted, and new intermediates and partial steps for its synthesis. The compounds are those of formula 1, wherein the substituents are as defined in the specification. |