abstract |
PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE, PHARMACEUTICAL KIT, METHOD FOR PREPARING COMPOSITION, AND USING COMPOSITION. The invention discloses a pharmaceutical composition for the controlled release of relatively toxic active compounds, in particular for interferon class bioactive proteins. The composition comprises a biodegradable block copolymer constructed from poly (ethylene glycol) terephthalate (PEGT) and poly (butylene terephthalate) (PBT). Composition is provided in the form of injectable microparticles, an injectable liquid that may have its own gel-forming properties or a solid implant. The invention further provides a pharmaceutical kit comprising the composition, methods for preparing the composition and the pharmaceutical uses thereof. |