abstract |
COMPOUNDS, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING A COMPOSITION, AND USE OF A COMPOUND. The invention relates to a group of novel phenylpiperazine derivatives with a dual mode of action inhibiting serotonin resorption and partial agonism at dopamine D2 receptors. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament which gives a beneficial effect. The compounds have the general formula (1): wherein the symbols have the meanings given in the specification and their tautomers, stereoisomers and N-oxides, as well as pharmacologically acceptable salts, hydrates and solvates of said compounds of formula (1) and their tautomers, stereoisomers and N-oxides. |