| abstract |
PYRIMIDINE DERIVATIVE Fused WITH NON-AROMATIC RING. Pyrimidine derivative or a pharmaceutically acceptable salt thereof, fused to a non-aromatic ring selected from dihydrothiophene, dihydrofuran, a cycloalkyl, etc .; and a pharmaceutical composition comprising any of the foregoing compounds as an active ingredient. These compounds exhibit excellent insulin secretion accelerating action and hyperglycemic action. Accordingly, pharmaceutical compositions comprising the above compounds as an active ingredient as a function of their actions are used in the therapy and / or prevention of insulin dependent diabetes mellitus (type 1 diabetes), insulin independent diabetes mellitus (type 2 diabetes), insulin resistant diseases, obesity, etc. |