| abstract |
UNSubstituted and substituted 4-benzyl-1,3-dihydroimidazole-2-thiones which act as specific or selective alpha2-adrenergic agonists and methods of their use. The present invention relates to compounds of formula 1: wherein the variables having the meaning defined in this specification are used to activate alpha-2-adrenergic receptors. The compounds of formula 1 are incorporated into the pharmaceutical compositions and are used as medicaments in mammals, including humans, for the treatment of diseases and / or for the alleviation of conditions that are responsive to alpha-2 -receptor agonist-mediated treatment. - adrenergic. |