http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0515935-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f874eb11d4775decc4fd06a6071a4c9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 |
| filingDate | 2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcac7f2edafada3fdeca3a0f781d06ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afddfc2348d1e8584384dbf36f1c0d36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0895f6a73b865e27a992183ecfa5c63 |
| publicationDate | 2008-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0515935-A |
| titleOfInvention | heterocyclyl- or 5-carbo substituted pyrimidines for hiv inhibition |
| abstract | "HETEROCYCLIL- OR 5-CARB PYRIMIDINS REPLACED FOR HIV INHIBITION". HIV replication inhibitors of formula (I), N-oxides, pharmaceutically acceptable addition salts, quaternary amines or stereoisomeric forms thereof, wherein: - a¬1¬ = a¬2¬ - a¬3¬ = a¬ 4¬ is -CH = CH = CH = CH-, -N = CH-CH = CH, -N = CH-N = CH-, -N = CH-CH = N, -N = N-CH = CH; -b¬1¬ = b¬2¬ - b¬3¬ = b¬4¬ is -CH = CH-CH = CH, -N = CH-CH = CH, -N = CH-N = CH, -N = CH-CH = N-, -N = N-CH = CH, -N = CH-CH = CH, -N = CH-N = CH, -N = CH-CH = N-, -N = N- CH = CH-; R¬1¬ is hydrogen; arila; formyl; Optionally substituted C1 -C6 alkyl; C 1-6 C 6 alkyloxycarbonyl; R¬2¬ is OH; halo; Optionally substituted C1 -C6 alkynyl; substituted carbonyl; carboxyl; CN; nitro; amino; substituted amino; polyhalomethyl; polyhlomethylthio; -S (= O) rR¬6¬; C (= NH) R¬6¬; R¬2¬ is CN; amino; substituted amino; Optionally substituted C1 -C6 alkyl; halo; C 1-6 alkyloxy C 1-6 alkyl optionally substituted; C 2-6 alkenyl or optionally substituted C 2-6 alkynyl; -C (= N-O-R 8) -C 1-4 alkyl; R¬7¬or -X ~ 3 ~ -R¬7¬; X 1 is -NR 1 -, -O-, -C (=)) -, CH 2 -, -CHOH-, S-, -S (= O) -; R¬3¬ is CN; amino; Optionally substituted C1 -C6 alkyl; -C (= N-O-R¬8¬) -C 1-4 alkyl; R¬7¬; -X ~ 3 ~ -R¬7¬; R¬4¬ is halo; OH; Optionally substituted C 1-6 alkyl; C 2-6 alkenyl or C 2-6 alkynyl; C 3-7 cycloalkyl; C 1-6 alkyloxy; CN; nitro; C 1-6 alkyl polyhalo; C 1-6 alkylalkoxy; substituted carbonyl; formyl; amino; mono- or di (C 1-4 alkyl) amino or R 7 '; R¬5¬ is -Y-C ~ q ~ H ~ 2q ~ -L or C ~ q ~ H ~ 2q ~ -Y-C ~ 2 ~ H ~ 2 ~ r-L; L is anila or Het; processes for preparing such compounds, pharmaceutical compositions comprising such compounds as active ingredients and the use of such compounds for the prevention or treatment of HIV infection. |
| priorityDate | 2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 38.