| abstract |
Benzyloxy derivatives as MAOB inhibitors. The present invention relates to compounds of general formula (I); where R¬ ¬ is halogen; R¬ ¬ is -C (O) NH ~ 2 ~, -C (NH ~ 2 ~) = N-OH, -C (O) CH ~ 2 ~ Br, -C (O) N (CH ~ 3 ~) OCH ~ 3 - or lower alkyl (O) -, or is a 5 membered heteroaryl group containing 2 or 3 heteroatoms selected from the group consisting of N, O or S, optionally substituted by R¬ ¬, where R ¬ ¬ is lower alkyl, -NRR "or -C (O) R; R is NR <R>," lower alkyl, or lower alkoxy; R < 3 > are independently hydrogen or lower alkyl; as well as pharmaceutically acceptable salts thereof for the treatment of diseases, which are mediated by monoamine oxidase B inhibitors, for example Alzheimer's disease and senile dementia. |