http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0513423-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1542e8802a0e6a7a8a7c6bd5627eb857 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 |
| filingDate | 2005-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52c46a32a67215c1b6d716a5c54e723b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5978921cfe8f6876da7167a8b11a3c24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_865abff4c943d914b30ede94f978c3b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cff3d49e753578164ebcb3830f043b86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38d6570143f3c3fbfeadede011c9b1c0 |
| publicationDate | 2008-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0513423-A |
| titleOfInvention | diphenylamine substituted salicyl thiazole derivatives and related compounds as phosphotyrosine phosphatase 1b (ptp1b) inhibitors for use as blood sugar lowering active substances for the treatment of diabetes |
| abstract | DIPHENAMINE SUBSTITUTED SALICILTIAZOLE DERIVATIVES AND COMPOUNDS RELATED TO PHOSPHYTROSIN 1B (PTP1B) INHIBITORS FOR USE WITH ACTIVE BLOOD SUGAR REDUCING SUBSTANCES FOR DIABETES TREATMENT. The present invention relates to compounds which develop a therapeutic effect to lower blood sugar. The compounds are particularly suitable for prevention and treatment of diabetes mellitus. The invention therefore relates to compounds of formula (I) wherein: R 1, R 2, R 3, R 4, R 5 independently of each other, H, F, CL, Br, I, OH, CF 3 ~, NO ~ 2 ~, CN, OCF ~ 3 ~, O- (C ~ 1 ~ -C ~ 6 ~) -alkyl, O- (C ~ 1 ~ -C ~ 4 ~) -alkoxy- (C ~ 1 (C 1 -C 4) alkyl, S- (C 1 -C 6) alkyl, C 1 -C 6 alkyl, C 2 -C 6 alkyl ) - (C 3 -C 8 -) alkenyl, cycloalkyl, O (C 3 - C 8) cycloalkyl, (C 3 - C 8) cycloalkyl, (C -C3-8-) -cycloalkenyl, O- (C3-3-8-) -cycloalkenyl, (C2-6-6) -alkynyl, aryl, O- (C1-6) aryl 1- (8C) -alkylene-aryl, O- (C-1-8C) -alkylene-aryl, S-aryl, CO-NH (C 1-6C-6) -alkyl , N (C 1 -C 6 -alkyl) 2, NH-SO 2 C H 3 SO 2 -CH 3 COOH, COO C 1 -C 6 ~) alkyl, CO-N ((C 1-1 -C 6) alkyl) -2; R 6: H, (C 1-1 -C 6) alkyl; A: A bond, -CH ~ 2 ~ -, -NH-, -CH ~ 2 ~ -O-, -S-, -CH ~ 2 ~ -CH ~ 2 ~ -, -CH (CH ~ 3 ~) - ; B: NH, NH (C 1 -C 4 -C) alkyl, NH (CO); D: phenyl, heterocycle; as well as physiologically compatible salts thereof. |
| priorityDate | 2004-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.