| abstract |
PROLINE AND MORPHOLINE DERIVATIVE COMPOUNDS. The present invention relates to compounds of formulas (I), (II), and (III), or a pharmaceutically acceptable salt thereof: where T is a (4 to 10) membered heterocyclyl selected from the group consisting of and where R1, R2 and R3 are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I), (II), and (III) and methods of treating a condition that is mediated by the enzyme 11- <hsd-1, the method comprising administering to a mammal an effective amount of a compound of formulas (I), (II), and (III). |