http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0510044-A

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filingDate 2005-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0510044-A
titleOfInvention pharmaceutical composition, kit, method for treating an individual, and use of a first and a second amount of one or more glucocorticoids
abstract PHARMACEUTICAL COMPOSITION, KIT, METHOD FOR TREATING AN INDIVIDUAL, AND USING A FIRST AND SECOND QUANTITY OF ONE OR MORE GLYCORTICOIDS. The invention relates to glucocorticoid replacement therapy and provides pharmaceutical compositions and kits designed to supply one or more glucocorticoids to an individual in need thereof in a manner that results in glucocorticoid serum levels that essentially mimic those of a healthy individual. for a clinically relevant period of time. The pharmaceutical composition comprises one or more glucocorticoids, wherein a first part of one or more glucocorticoids is substantially and immediately released over a prolonged period of at least about 8 hours, and the amount of one or more glucocorticoids of the first part, expressed as hydrocortisone equivalents, is in the range of about 15 to about 50% of the total hydrocortisone equivalents. The invention also relates to a method of treating diseases requiring glucocorticoid treatment, such as in individuals having a glucocorticoid deficiency disorder. In another aspect, the invention relates to the use of a first and a second amount of one or more glucocorticoids for the preparation of a pharmaceutical composition or kit for treating a glucocorticoid deficiency disorder.
priorityDate 2004-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 28.