| abstract |
"Triazole Derivatives That Inhibit VASOPRESSIN ANTAGONIST ACTIVITY" Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein Het represents 2-pyrimidinyl or 2-pyridinyl; R1 represents H, C1-3 alkyl, or a nitrogen-containing heterocyclic ring; R 2 represents H, C 1-1 alkyl-benzyl and R 3 represents H, methyl, methoxy or chlorine; anxiety, cardiovascular disease (including angina, atherosclerosis, hypertension, heart failure, edema, hypernatremia), dysmenorrhea (primary and secondary), endometriosis, emesis (including motion sickness), intrauterine growth retardation, inflammation (including rheumatoid arthritis) , mittlesmerchz, preeclampsia, premature ejaculation, premature labor (preterm) and Raynaud's syndrome. |