http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0502016-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6085cc981958ccb9f6c9c0b5ead9f539 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4741 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2005-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3b721535e2bd290e3c6b217ca0e8676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360e78f3f3479d8498dffd86b529a140 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_838450186821eba39f70440880947f00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbf3112e52b46e6bd6e721c81ca15179 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d05740d213e863567902c5e5b13df85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_652ef763356c9524d5e0b6564b53d241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66e92e8935d2d66e51a6f747c2a01f20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c5291ace496f970f39fe1a03cf68c8c |
| publicationDate | 2007-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0502016-A |
| titleOfInvention | urea compounds, pharmaceutical compositions containing them and their use in the treatment of inflammatory diseases |
| abstract | "UREDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND ITS USE IN THE TREATMENT OF INFLAMMATORY DISEASES". The present invention discloses functionalized ethyl 6-N-alkyl and / or 6-N-aryl ureas ¢ 1,3-dioxolo ¢ 5,4-g-quinoline-7-carboxylate derivatives (3a-z, 4a-z); and congeners (5a-z) of general formula (I, II, III and IV), useful in the treatment and / or prevention of diseases of inflammatory origin, such as acute or chronic inflammatory conditions, different types of arthritis. , asthma, Crohn's disease and type I diabetes mellitus, among others. These derivatives have the ability to modulate the inflammatory process by acting at the level of the p-38 mitogen-activated protein kinase (MAPK-p38). Moreover, the derivatives of the present invention exhibit significant anti-inflammatory properties measured in in vivo models. The present invention also discloses processes for producing such derivatives and pharmaceutical compositions containing them. |
| priorityDate | 2005-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.