abstract |
"PYRIDINYL METHANONE COMPOUNDS REPLACED BY AMINO USEFUL IN THE TREATMENT OF KINASE DISORDERS". The present invention provides amino substituted pyridinyl methanone compounds; pharmaceutical compositions comprising the compounds and the processes for their synthesis. The compounds, which are cyclin dependent kinase (CDK) inhibitors, may be used to treat or ameliorate CDK-mediated disorders. The invention thus also provides for the therapeutic or prophylactic use of the compounds and / or pharmaceutical compositions to treat such disorders. |