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filingDate 2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17c2c81dadfa3f3efb4eeaa742967ad3
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publicationDate 2007-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0414857-A
titleOfInvention dmbt1 as a clinical marker and its use
abstract "DMBT1 AS A CLINICAL MARKER AND ITS USE". The present invention provides methods for determining the estrogenic activity of a compound, while including contacting an estrogen responsive system having a gene under the control of a DMBT1 regulatory sequence with a test compound and determining how the test compound affects expression of the estrogen. gene. The invention further provides the determination of progestogenic activity of a compound, which includes contacting an estrogen and progesterone responsive system having a gene under the control of a DMBT1 regulatory sequence with an estrogenic activity and a test compound and determining how the compound of test effects gene expression. Nucleic acids and cell-based systems that include a portion of the DMBT1 regulatory sequence useful for these methods are also provided.
priorityDate 2003-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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