abstract |
"PURINE DERIVATIVES INHIBITING HIV REPLICATION". The present invention relates to the use of a compound of formula (I) for the manufacture of a medicament for the prevention or treatment of HIV infection wherein the compound of formula (I) is a compound of formula (I), a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine or a stereochemically isomeric form thereof, wherein A and B each represent a radical of formula (a) or (b) and wherein -CD- represents a radical bivalent of formula -N = CH-NR¬ 17¬- (c-1); or -NR¬ 17¬-CH = N- (c-2); provided that when A represents a radical of formula (a) then B represents a radical of formula (b) and when A represents a radical of formula (b) then B represents a radical of formula (a). |