abstract |
"Quinazoline derivative, compound, process for the preparation of a quinazoline derivative, pharmaceutical composition, use of a quinazoline derivative, and a method for producing an anti-proliferative effect in a single animal". The invention relates to quinazoline derivatives of Formula each of R 1a, R 1b, R 2 and R 3 having any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them, and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumors that are sensitive to inhibition of erbB receptor tyrosine kinases. |