abstract |
"benzimidazole derivatives: preparation and pharmaceutical applications". the present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. more specifically, the present invention relates to benzimidazole-containing compounds to methods for their preparation. these compounds may be useful as medicaments for the treatment of proliferative disorders, as well as other diseases encompassing deregulation of histone deacetylase (hdac), or are related or associated with such deregulation. |