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filingDate 2004-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_959902a9b0cc04211b68b9382ce244ca
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publicationDate 2006-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0414386-A
titleOfInvention compound, methods of manufacturing the same, for treating or preventing a disease, for activating er function in a bone cell, for inhibiting er function in a cell, for inhibiting il-6 expression, for inhibiting growth of an er-expressing neoplastic cell, for prevention of spermatogenesis, for prevention of an adverse reproductive effect associated with exposure to a lack of natural or chemically environmental hormonal balance, and, composition
abstract "COMPOSITE, METHODS FOR MANUFACTURING THE SAME, FOR TREATMENT OR PREVENTION OF A DISEASE, FOR ACTIVATION OF ER FUNCTION IN A BONE CELL, FOR INHIBITION OF ER FUNCTION IN A CELL, FOR INHIBITION OF THE EXPRESSION FOR ILL-INITION, 6 GROWTH OF A NEOPLASIC CELL EXPRESSING ER, FOR PREVENTION OF SPERMATOGENESIS, FOR PREVENTION OF AN ADVERSE REPRODUCTIVE EFFECT ASSOCIATED WITH EXPOSURE TO A LACK OF NATURAL OR CHEMICAL ENVIRONMENTAL, AND "COMPOSITION". Benzopyranone compounds having the following structure: wherein R 1, R 2, X, Y and n are as defined herein are described. Benzopyranone compounds are usable for the treatment or prevention of a bone resorption disease, a neoplastic disease, arthritis, an estrogen-exacerbated disease, or an estrogen-enhanced disease, comprising administering an effective amount of a compound. benzopyranone to a patient in need of treatment or prevention; activation of estrogen receptor ('ER') function in a bone cell; inhibition of ER function in a cancer cell; inhibition of interleukin-6 ('IL-6') expression in a cell; and inhibiting the growth of a neoplastic cell, comprising contacting the cell with an effective amount of a benzopyranone compound.
priorityDate 2003-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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