abstract |
"BENZOILGUANIDINES REPLACED BY PENTAFLUORSULFANILPHENYL, PROCESS FOR PREPARATION, HIRING AS A MEDICINAL PRODUCT OR DIAGNOSTIC, AS A MEDICINAL PRODUCT CONTAINING THEM". The present invention relates to pentafluorsulfanylphenyl substituted benzoylguanidines of formulas I and II, wherein R1, R1, R2, R2, R3, R3, R4 and X have the meanings indicated in the claims, which are suitable as antiarrhythmic drugs with cardioprotective components for prophylaxis of infarction and treatment of infarction as well as for treatment of angina pectoris. They also preventively inhibit pathophysiological steps in the onset of ischemic-induced damage, particularly in causing ischemic-induced cardiac arrhythmias. |