| abstract |
"cd20 binding polypeptide compositions". The present invention relates to polypeptide compositions that bind to cd20 antigen, especially human cd20 antigen. Polypeptide compositions have the biological activity of known anti-cd20 antibodies, such as 2b8 or leu16, but show reduced immunogenicity when compared to unmodified molecules. polypeptide compositions include chimeric antibodies, antibody fragments and fusion proteins of an antibody or antibody fragment with a cytokine. |