| abstract |
"combinations of vasoactive agents, their use in the pharmaceutical and cosmetic field and formulations containing them". the present invention relates to combinations of vasoactive substances acting at the venous or arterial level with phosphodiesterase inhibitors, including phosphodiesterase v, in particular: visnadine or esculoside; at least one compound selected from icarin or its derivatives or extracts containing them, ginkgo biloba dimeric flavones either in free form or complexed with phospholipids, amentoflavone; at least one compound selected from escin, beta-sitosterol escin complexed with phospholipids, sericoside, sericoside complexed with phospholipids or centella asiatica extract in free form or complexed with phospholipids. the formulations according to the invention are useful in reducing panicopathy and the problems associated with venous insufficiency of the lower limbs. |