| abstract |
"serum cholesterol lowering agent or preventive or therapeutic agent for atherosclerosis, and method of dosing a serum cholesterol lowering agent or preventive or therapeutic agent for atherosclerosis". The invention relates to a serum cholesterol lowering agent or a preventive or therapeutic agent for atherosclerosis, each comprising a combination of a compound represented by the following general formula (i) or pharmaceutically acceptable salts with a cholesterol biosynthesis and / or fibrate-like cholesterol lowering agent. [in the formula a ~ 1 ~, a ~ 2 ~, a ~ 3 ~ and a ~ 4 ~ are each hydrogen, a group represented by formula (b), or a group represented by formula (a) provided that at least one of these is a group represented by the formula (a): a2 is C1 -C5 alkyl etc; and n, p, q and r are each an integer of 0, 1 or 2. |