| abstract |
"IMMEDAZOLE DERIVATIVES SUBSTITUTED BY HETEROARIES AS GLUTAMAT RECEPTOR ANTAGONISTS". The present invention relates to imidazole derivatives of the general formula (I). wherein R¬ 1¬, R¬ 2¬, R¬ 3¬ and R¬ 4¬ are as defined in the specification, as well as pharmaceutically acceptable salts thereof, and processes for their preparation. The invention also relates to the use of said imidazole derivatives for the preparation of medicaments and the medicaments containing them for the prevention or treatment of mGluR5 receptor mediated disorders, such as acute and / or chronic neurological disorders, particularly anxiety, or for the treatment of chronic and acute pain. |