abstract |
"PHARMACEUTICAL COMPOSITION, DOSAGE UNIT FORM AND METHODS TO PREPARE YOUR USE". The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one release agent compound and at least one YY peptide (PYY) and a PYY agonist. Preferably, the composition includes a therapeutically effective amount of peptide YY or PYY agonist and release agent compound. The composition of the present invention facilitates the release of PYY, a PYY agonist, or a mixture thereof and increases their bioavailability compared to administration without the release agent compound. PYY and PYY agonists have activity as agents to reduce nutrient availability, including reducing food intake. |