| abstract |
"TETRAHYDROISOQUINOLINE DERIVATIVES AS PPAR- <244> ACTIVATORS". PPAR alpha activators, pharmaceutical formulations containing such compounds and the use of such compounds to increase certain levels of plasma lipids, including high-density lipoprotein cholesterol, and to decrease levels of certain other plasma lipids, such as cholesterol. LDL and triglycerides and therefore to treat diseases which are exacerbated by low levels of HDL cholesterol and / or high levels of LDL cholesterol and triglycerides, such as atherosclerosis and cardiovascular disease, in mammals, including humans. |