abstract |
"METHODS FOR IDENTIFYING A COMPOUND, TREATING OR PREVENTING A DISEASE OR DISORDER IN A HUMAN, INCREASING THE FUNCTION OF ORGANS, TISSUES OR CELLS EXCITABLE IN A HUMAN COMPLEX COMPLEX ACTIVITY A HUMAN ". The present invention relates to methods for identifying compounds that exhibit tissue protective activity using heteromultimer receptor complex that mediates tissue protective activities. The complex consists of at least one EPO-R complex with at least one? These compounds used in assays to identify tissue protective compounds include, but are not limited to, small molecules and biolocytes. The compounds identified using these assays may be employed to treat or prevent various diseases, disorders, or conditions of the central and peripheral nervous systems and also those of other excitable or erythropoietin responsive organs, tissues, and cells. |