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publicationDate 2006-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0409263-A
titleOfInvention compound; pharmaceutical composition; method for treating an ikk-mediated disease and method for inhibiting ikk in a patient in need of it
abstract "COMPOUND; PHARMACEUTICAL COMPOSITION; METHOD FOR TREATING IKK-MEDIATED DISEASE AND METHOD FOR INHIBITING IKK IN A PATIENT YOU NEED". This invention provides beta-carboline compounds of formula I: wherein Ring A is a pyridinyl, pyrimidinyl, morpholinyl, piperidinyl, piperazinyl, pyrrolidinyl, pyranyl, tetrahydrofuranyl, cyclohexyl, cyclopentyl or thiomorpholinyl ring, and R¬ 1¬ , R¬ 2¬ and R¬ 3¬ are as described in the descriptive report. The compounds are inhibitors of IKK-2, which are useful for treating IKK-2 mediated diseases, such as inflammatory diseases and cancer.
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Total number of triples: 39.