| abstract |
"PIRROL ยข 1,2-B COMPOUNDS! PYRIDAZINE AND ITS USES AS CFR-1 RECEIVER ANTAGONISTS". The present invention relates to novel CRF receptor antagonists and their use as a treatment for various disorders comprising disorders manifesting CRF hypersegregation or associated with CRF or CRF receptors such as anxiety and depression. CRF receptor antagonists of the invention have the structure of formula (I): Including stereoisomers or mixture of stereoisomers, pharmaceutically acceptable prodrugs or pharmaceutically acceptable salts thereof, wherein in formula (I) R is H or Me. |