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filingDate 2004-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecbe04542c441327553db24fa0e12d47
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publicationDate 2006-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0408526-A
titleOfInvention a pharmacologically acceptable copolymer or salt thereof, pharmaceutical composition, modifier capable of modifying a complex protein or analogue or variant thereof, methods for prolonging the time that a protein or analog or variant thereof is retained in the blood stream following administration to a patient, and for the treatment or prophylaxis of a disease in a patient who is susceptible to a protein or an analog or variant thereof, and, use of the complex
abstract "COPOLYMER OR A SALT OF THIS PHARMACOLOGICALLY ACCEPTABLE, PHARMACEUTICAL COMPOSITION, MODIFIER ABLE TO MODIFY A PROTEIN OR ANALOG OR VARIANT OF THIS, COMPLEX, METHODS TO EXTEND THE TIME IN WHICH A PROTEIN IS NOT INTENDED WITH THE ANALYZE TO A PATIENT, AND FOR THE TREATMENT OR PROPHILAXY OF A DISEASE IN A PATIENT THAT IS SUSTAINABLE TO A PROTEIN OR ANALOG OR VARIANT OF THIS AND USE OF THE COMPLEX ". A pharmacologically acceptable copolymer or salt thereof is provided which contains, as constitutional units, (a) one or more structural units of formula (I): wherein m is an integer from 3 to 100, Alq represents alkylene and R¬ 1¬ and R¬ 2¬ are the same or different and each represents optionally substituted hydrogen or alkyl and (b) one or more structural units of formula (II): wherein R¬ 3¬ represents hydroxyl, optionally substituted alkoxy, aryloxy optionally substituted or a group represented by the formula -NR¬4¬R¬5¬, wherein R¬4¬ and R¬5¬ are the same or different and each represents optionally substituted hydrogen or alkyl. There is further provided a pharmaceutical composition comprising said copolymer, a protein modifier comprising said copolymer, a complex of said copolymer with a protein, a method of preventing or treating disease using said complex, the use of said complex in manufacturing of a medicament for preventing or treating diseases and methods for the synthesis of said copolymers and said complexes.
priorityDate 2003-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
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Total number of triples: 34.