| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab6f907da23c9c792d65fb63fb6893a8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-292 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 |
| filingDate |
2004-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a429b51cc014de8f69a697ed1f36d6c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe35fc5f21e25dabdd469c8b300e7eb0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e3fe5130c05c8e2194581b53ced99e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc860a8bd2a7911041de9a43a3cac2b |
| publicationDate |
2006-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-PI0407632-A |
| titleOfInvention |
method for treating chronic hepatitis, recombinant hsc chimeric protein molecule, and method for enhancing the production of one or more of the cd8 +, cd 4 + t cells that produce gamma and cytotoxic t lymphocytes against hepatitis b virus. |
| abstract |
"METHOD FOR TREATING CHRONIC HEPATITIS, RECOMBINANT HBC CHEMICAL PROTEIN MOLECULATION, AND METHOD FOR INCREASING ONE OR MORE CD 8+, CD 4+ T CELLS WHICH PRODUCE BITROXY VITROCYTES TYPOTHYTES " A method for treating chronic hepatitis B is disclosed which comprises administering a T cell stimulation amount of a vaccine to a patient. The vaccine comprises an immunogenic amount of chimeric, carboxy terminal (HBc) truncated hepatitis B virus nucleocapsid protein (nucleus) that is engineered for both the marked stability of self-aggregating particles and the substantial absence of nucleic acid binding. for these particles. The chimeric protein molecule may include one or more peptide-linked immunogenic epitopes at one or more of the N-terminus, the immunogenic loop or the C-terminus of HBc. The marked stability of the self-aggregating particles is achieved by the presence of at least one heterologous cysteine residue near one or both of the amino terminus and the carboxy terminus of the chimeric molecule. |
| priorityDate |
2003-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |