abstract |
"calcitonin gene-related peptide receptor antagonists". The present invention relates to compounds of formula (I) as calcitonin gene-related peptide receptor antagonists ("cgrp receptor"), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment employing and their use in therapy for the treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, menopause stimulation, inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), and other treatment conditions which may be performed by the cgrp receptor antagonist. |