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filingDate 2001-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d63d2afe87df1ee49d3ba2108bbd7716
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publicationDate 2015-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0116945-B1
titleOfInvention prepared for local treatment of hyperproliferative epithelium
abstract "drug for prevention of restenosis". The invention relates to a preparation for preventing restenosis. So far known restenosis prevention preparations do not achieve sufficient active agent concentrations in the affected sections of the vascular walls as higher doses cause undesirable side effects. The present invention is a preparation to which at least one antihyperplastic agent is added and having a distribution ratio of butanol to water of <0.52. The lipophilic active agent is rapidly absorbed by the vascular wall and in sufficient quantity. The preparation may be a liquid that can pass through capillaries and may contain a contrast agent so that the active agent is transferred into the vascular wall without any additional effort while taking the necessary contrast radiographs. The preparation may also be applied to a catheter.
priorityDate 2001-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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