| abstract |
Invention Patent: <B> "PIRROLEUM COMPOUNDS [2,3-d] PYRIMIDINE" <D>. Compounded with the formula in which R¹, R² and R³ are as previously defined, which are inhibitors of the enzymes protein tyrosine kinases such as Janus Kinase 3 and as such are a useful therapy as immunosuppressive agents for organ transplants, lupus, multiple sclerosis, arthritis rheumatoid, psoriasis, Type I diabetes and complications of diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid diseases, ulcerative colitis, Crohn's disease, Alzheimer's disease, leukemia and other autoimmune diseases. |