http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-9911178-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate | 1999-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c003d994ad83a762dbcd17ab87ccbd42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f02eadb7dd685b522cf7ff0db7298fa9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_033f175937882d6b6bacfb34695a95bb |
| publicationDate | 2001-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-9911178-A |
| titleOfInvention | Derivatives of 3- (2-oxo- [1,3 '] bipyrrolidinyl-3-ylidenomethyl) -cefems |
| abstract | Invention Patent: <B> "DERIVATIVES OF 3- (2-OXO- [1,3 '] BIPIRROLIDINYL-3-ILIDENOMETHYL) -CEFEMS" <D>. The present invention relates to new compounds of the formula (I) in which R ^ 1 ^ is hydrogen, C ~ 1-6 ~ alkyl, optionally substituted by fluorine, or C ~ 3-6 ~ cycloalkyl; R ^ 2 ^ is hydrogen or a group selected from -CH ~ 2 ~ C (= CHR) -COOR, -CH ~ 2 ~ OCOR, -CH (R) OCOR, -CH (R) OCOOR, -CH (OCOR) OCOR, -CR ~ 2 ~ COCH ~ 2 ~ OCOR and (II); R ^ 3 ^ is hydrogen or a group selected from -CH ~ 2 ~ C (= CH ~ 2 ~) -COOR, -COOCH ~ 2 ~ C (= CHR) -COOR, -COOCH ~ 2 ~ OCOR, -COOCH (R ) OCOR, -COOCH (R) OCOOR, -COOCH (OCOR) OCOR, -COOCH ~ 2 ~ COCH ~ 2 ~ OCOR, and (III); with the proviso that one of R ^ 2 ^ and R ^ 3 ^ is hydrogen and the other of R ^ 2 ^ and R ^ 3 ^ is different from hydrogen, R is hydrogen or C ~ 1-6 ~ alkyl; R ^ 4 ^ is hydrogen or hydroxy, R ^ 5 ^ is hydrogen or <SYM> -hydroxyalkyl; and X is CH or N, as well as to pharmaceutically acceptable salts of said compounds and hydrates of said compounds and their salts, and to the use of compounds of formula (I) and pharmaceutically acceptable salts of said compounds and hydrates of said compounds and salts for the manufacture of pharmaceutical preparations containing such compounds. |
| priorityDate | 1998-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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