http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-9909197-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-66 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 |
| filingDate | 1999-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7757ef2d4bf123ae90dbdd758418436c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23da23cc5f6b0fd065a1d7704b76836d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c993519c4cc61aaa2920228e533f50eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ea1b420cb8f38ead140ed465124a0bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd353bc9b009350567061c9d0ce4b4a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3ccb0d84506e3b24880608cb3e4010a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_365d6c008ac0e8dce16ca0477eba79ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ad34b861ad2e616348197a155504f17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db1c30ca5d5a6229c66afccb1eb5c16e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39c877cd5f3e3d1693817ca5555b717a |
| publicationDate | 2000-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-9909197-A |
| titleOfInvention | Tri-substituted 1,3,5-triazine derivatives for the treatment of HIV infections |
| abstract | Invention Patent: <B> "TRI-SUBSTITUTE 1,3,5-TRIAZINE DERIVATIVES FOR THE TREATMENT OF HIV INFECTIONS" <D>. The present invention relates to the use of the compounds of formula (I) the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, where A is CH, CR4 or N; n is 0, 1, 2, 3, or 4; R¹ and R² are each independently selected from hydrogen, hydroxy, C ~ 1-12 ~ alkyl, C ~ 1-12 ~ alkyloxy, C ~ 1-12 ~ alkylcarbonyl, C ~ 1-12 ~ alkyloxycarbonyl, aryl, amino, mono- or di (C ~ 1-12 ~ alkyl) amino, mono- or di (C ~ 1-12 ~ alkyl) aminocarbonyl, where each of the aforementioned C ~ 1-12 ~ alkyl groups can optionally, and individually be replaced; or R¹ or R² taken together, can form pyrrolidinyl, piperidinyl, morpholinyl, azido or mono- or di (C ~ 1-12 ~ alkyl) amino-C ~ 1-4 ~ alkylidene; R³ is hydrogen, aryl, C ~ 1-6 ~ alkylcarbonyl, C ~ 1-6 ~ alkyl, C ~ 1-6 ~ alkyloxycarbonyl, C ~ 1-6 ~ alkyl substituted with C ~ 1-6 ~ alkyloxycarbonyl; and each R ~ 4 ~, independently, is hydroxy, halo, C ~ 1-6 ~ alkyl, C ~ 1-6 ~ alkyloxy, cyano, aminocarbonyl, nitro, amino, trihalomethyl, or trihalomethyloxy; L is -XR ^ 5 ^ or -X-Alq-R ^ 6 ^, where R ^ 5 ^ and R ^ 6 ^ are each, independently, indanyl, indolyl or phenyl, each of the indanyl, indolyl or phenyl groups being able to be replaced; and X is -NR ^ 3 ^ -, -NH-NH-, -N = N-, -O-, -S-, -S (= O) - or -S (= O) ~ 2 ~); aryl is optionally substituted phenyl; Het is an optionally substituted heterocyclic aliphatic or aromatic radical for the production of a drug to treat individuals suffering from HIV infection (Human Immunodeficiency Virus). The invention also relates to new compounds that are a subgroup of the fields of formula (I), their preparation and the pharmaceutical compositions that comprise them. |
| priorityDate | 1998-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.