abstract |
"COMPOUND, PHARMACEUTICAL COMPOSITION, AND, PROCESSES TO INHIBIT THE RELEASE OF LUTEINIZATION HORMONE (LH) IN A MAMMALIAN IN NEED OF SUCH TREATMENT AND TO PREPARE A COMPOUND". Derivatives of 3 ', 3'-N-bisdesmethyl-3', 3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic erythromycin A bamate of formula (I) are disclosed, which are antagonists of the hormone that releases the lutenizing hormone (LHRH). Pharmaceutical compositions comprising the compounds, the processes of using the compounds and the process of making them are also disclosed. |